Why Aren’t Plain GLP-1s Producing the Results You Hoped For?
Why Liraglutide and Dulaglutide Often Disappoint Without Support — and What You Can Do About It
Many patients begin GLP-1 therapy with high hopes — only to experience disappointment, slower weight loss, or early plateaus when using liraglutide or dulaglutide alone.
These medications are clinically proven to support weight loss. But when used without any added metabolic support, they’re often not enough — especially for patients coming off stronger GLP-1s like semaglutide or tirzepatide.
Let’s explore why this happens — and how the right support, like SLM+, can make a meaningful difference.
1. Plain GLP-1s Only Target One Hormone
Semaglutide and tirzepatide work so well because they:
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Suppress appetite
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Slow gastric emptying
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Improve insulin sensitivity
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Activate multiple hormonal pathways
By contrast:
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Liraglutide and dulaglutide only activate GLP-1 receptors
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Tirzepatide, by comparison, activates both GLP-1 and GIP
🔬 The result:
With plain GLP-1s, your metabolism doesn’t receive the same level of multi-hormonal support, and progress slows.
2. Weight Loss Plateaus Are More Common
On liraglutide alone, patients typically lose:
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~8% of body weight in 12 months
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Compared to ~15–20% with newer therapies
For many, this leads to:
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Stalled progress around month 3–6
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Increased cravings and hunger
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Frustration and decreased motivation
3. Liraglutide Requires Daily Injections — Which Can Undermine Compliance
Compared to weekly options like semaglutide, liraglutide’s daily injection schedule increases the risk of:
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Missed doses
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Injection fatigue
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Reduced consistency
Without consistent dosing, results decline further.
4. Insulin Resistance May Remain Untreated
Plain GLP-1s can reduce glucose levels, but they don’t address the root cause of:
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Insulin resistance
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Post-meal spikes
- Metabolic inflexibility
This is where SLM+ offers a science-backed advantage.
How SLM+ Helps You Break Through the Limitations
SLM+ by STAAR LABS is a GLP-1 support supplement formulated specifically to help patients on plain GLP-1s like liraglutide and dulaglutide achieve better outcomes.
🌿 What’s Inside:
Together, these ingredients:
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Extend weight loss momentum
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Support multi-pathway metabolic signaling (GLP-1 + GIP-like effects)
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Help reduce blood sugar spikes and insulin resistance
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Prevent plateaus and improve overall satisfaction
Real-World Results
SLM+ makes liraglutide work like a modern therapy — not a step backwards.
Learn more about how SLM+ fits into our GPS Protocol (GLP-1 + Pramlintide + SLM+).
What to Do Next
✅ Patients: Ask your provider or pharmacy if they carry SLM+ or order directly from STAAR LABS.
✅ Clinics & Pharmacies: Learn about our wholesale program and provider implementation support.
✅ Providers: Download our upcoming protocol guide for SLM+ + Liraglutide integration.
Don’t let older GLP-1s limit your progress. SLM+ is the key to unlocking modern results from legacy medications.
🛡 Disclaimers
Medical Disclaimer:
This blog is for informational purposes only and is not intended as medical advice. Always consult your healthcare provider before making any changes to your medications, supplements, or health regimen. Individual results may vary.
Supplement Disclaimer:
Statements regarding dietary supplements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Research & Innovation Disclosure:
STAAR LABS conducts protocol development in collaboration with licensed providers and pharmacies. Our research focuses on combining nutraceutical and pharmaceutical interventions to enhance metabolic outcomes. Weight loss projections involving SLM+ are based on early observational feedback and theoretical mechanisms, not yet published in peer-reviewed clinical trials.
